Biodegradable electronics offer a promising path toward sustainable and environmentally responsible technologies. Unlike conventional electronics, these systems are designed, built, and operated using materials engineered to safely decompose upon use, making them ideal for applications in transient environments such as biomedical implants, environmental sensors, and transient consumer devices. Existing computing paradigm, however, are often inherently not fit for computing with biodegradable electronics. Established concepts, abstractions, and system implementations cannot be re-used as is. We focus the research in the development of software strategies to support biodegradable components, with particular emphasis on two key areas: biodegradable non-volatile memories (NVMs) and batteries. These components are crucial for the long-term functionality of embedded systems, yet their biodegradable nature entails limited reliability, constrained capacity, limited data retention, and non-standard behavior during operation. We investigate biodegradable electronics combined with intermittent computing systems, which are designed to operate under conditions of frequent power loss. Our approach centers on enhancing system resilience and ensuring continued progress despite hardware degradation, as state retention in non-volatile memories is fundamental.